LGD 3303 Review: How Strong is this SARMS?

LGD 3303 Overview

Gather around people. There’s a new kid on the block. LGD-3303 is the latest addition to the SARMs (selective androgen receptor modulators) family. Word is, this newcomer packs a mean punch! Ever since the advent of SARMs in the market, the hype around these new generation synthetic drugs has not cooled off. While the hype may make you want to jump on the SARMs, or in particular the LGD-3303 bandwagon, it would be prudent if you acquainted yourself with the substance’s mechanics first.

So, LGD-3303 is pretty fresh on the market, and so are its SARMs siblings. Therefore, the info on these compounds isn’t exactly abundant, but we’ve managed to compile a comprehensive guide on LGD-3303 of the good stuff and the dirt as well.

What is LGD 3303?

LGD 3303 is a SARM developed to prevent muscle wasting and manage osteoporosis. It is a non-steroidal compound that is administered orally. LGD-3303 binds to the androgen receptors on a cell with an exceptionally high affinity and selectivity. Regarding its androgenic properties, it is a full agonist on muscle and a partial agonist on the prostate.

LGD-3303 was developed to address a broad range of issues. However, for this context, it is utilized for its ability to enhance muscle mass and bone density with minimal undesirable effects. While the selective action of LGD-3303 and SARMs other is still unclear, it is a significant leap from the typical anabolic steroids. Once LGD-3303 is administered into the body, it triggers androgenic action on a cellular level.

However, it is crucial to remember that the human body has millions if not billions of cells and provoking androgenic action on all of them could have some pretty drastic side effects. For that reason, LGD-3303 is a selective receptor, which only targets the cells in the muscle and skeletal tissues.

The effect of LGD-3303 on the muscle and skeletal tissues has made it a favorite for athletes and bodybuilders and is also a potential treatment for people with bone density problems such as osteoporosis.

LGD-3303 is a non-steroidal, orally active SARM, and while it has significant muscle building impacts and high androgenic action, it has little effects on the body’s androgenic organs.

LGD 3303 History

LGD-3303 is under the research and development of a company known as Ligand Pharmaceuticals. This compound has a chemical structure that closely resembles another one of Ligand’s SARMs, LGD 4033. However, LGD-3303 is not as readily available as is the former.

Ligand pharmaceuticals embarked on the pre-clinical research for SARM LGD-3303 in 2007, at the American Society for Bone and Mineral Research Annual Meeting. Subsequently, the manufacturer has conducted numerous clinical studies on LGD-3303, and the findings so far indicate a tremendous potential to enhance muscle mass and prevent wasting of muscle. While it may be argued that other SARMs have realized similar impacts, it is evident that LGD-3303 may be more effective.

Moreover, LGD-3303 can trigger various aspects of female behavior and is a potential treatment in women with sexual desire disorders. Furthermore, this compound enhances the effectiveness of bisphosphonate medication (a medicine used to prevent and cure loss of bone density).

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Speeds up Metabolism

LGD 3303 has a significant positive effect in enhancing metabolic action. This is a considerable benefit, especially for people who want to cut fat. Therefore, you can leverage LGD 3303 in your cutting cycle and achieve your fat loss objectives. Moreover, it is advisable to stack LGD 3303 with other similarly effective SARMs and adhere to a vigorous workout regimen for the best fat loss results.

Doesn’t affect Androgenic Organs

This is probably the most significant benefit of LGD 3303. The fact that it provides androgenic activity without interfering with the androgenic organs is a huge plus. If you consider anabolic compounds that were used for similar purposes, you will realize a considerable difference. For instance;

  • This sarm does not impact the size of the prostate gland
  • It doesn’t interfere with the endogenous testosterone production
  • These sarms bears zero virilization risks, meaning that women can use it safely

However, to be on the safe side, women who want to use LGD 3303 should consult a physician.

Increase Muscle mass

LGD-3303 has demonstrated a remarkable potential to help you build muscle mass. As a bodybuilder, or just someone looking to increase their muscle mass, this is a huge plus. LGD-3303 enhances your muscle’s ability to retain nitrogen, which makes them grow tremendously.

Nitrogen is an essential component when building muscle because it enhances protein synthesis. As you may know, muscles require substantial amounts of protein to grow. Ultimately, more nitrogen, more protein, and eventually, more muscle mass.

Enhance Bone Density

Numerous clinical tests have been conducted on the ability of LGD-3303 to enhance bone density. Findings indicate that this compound can help in the management of osteoporosis, although there isn’t sufficient evidence to back its ability to prevent or cure brittleness. However, since LGD-3303 does enhance bone density to some extent, it helps to increase your range of motion as an athlete and also your muscular endurance and strength.

Side Effects

So far, so good. LGD-3303 has not demonstrated any adverse side effects during its clinical trials. However, LGD-3303 has exhibited some mild side effects, although they may not be generalized.

Some people may exhibit digestive issues during the first one or two days of use.

There may also be a slight reduction in one’s energy levels, although the opposite is also possible. However, when the effects of the drug wear off, it is not uncommon for a user to experience depleting energy.

Changes in appetite are not unheard of, although they only occur in transient experiences.

The said side effects are primarily due to the tolerance level, which, as you may know, varies with every individual. While you may feel tempted to up the dose for the best results, it is advisable that you adhere to the instructed minimum and increase the dosage as you build more tolerance.

Is PCT Necessary After Using LGD-3303?

Following what we’ve learned about the side effects posed by LGD-3303, it suffices to state that Post Cycle Therapy is not necessary after using LGD-3303. Unlike anabolic steroids that pose a significant threat to the body’s endogenous testosterone production, LGD-3303 is friendly to the gonads.

Therefore, after using LGD-3303, you can resume your normal activities without the need to even out your hormones, which isn’t the case after completing an anabolic cycle.

LGD 3303 is the only active ingredient in this compound, although you should check the product label for more information on the ingredients. 

Price & Purchase

At the moment, there is no real LGD-3303 in the market, as the product is still under development. However, there is a horde of websites claiming to have it in their inventory, and you must be very careful with these. If you are reckless, you may end up buying a fake, a completely different SARM, or even a prohormone.

LGD-3303 is still in its developmental stages, which is why it is not readily available for commercial use.

If you like the LGD-3303 review and feel that you want it immediately, it is advisable that you buy LGD-4033. This is the SARM with the closest chemical resemblance to LGD-3303, and it is also from the same manufacturer.

Again, it is always advisable to buy from the manufacturer’s given that this drug is entirely legal, to avoid purchasing counterfeits.


LGD-3303 has a comparatively short half-life of about 6 hours. Therefore, if you want to maintain stable concentrations of the drug in your system, you should dose the SARM frequently. 

The recommended dose for this LGD-3303 SARM is three to four doses per day. However, then the dosage is contingent on the purpose you have in mind. Also, given that the product is still under development, you may have to adjust your dosage in the future.

However, it is said that you may experience significant results at 10 mg, while most people claim that the sweet spot lies between the 15 mg and 20 mg range.

If you are on a cutting cycle, 15 mg to 20 mg per day is the recommended dose for a six to eight-week cycle. On the flipside, if you are bulking and want optimum results, you are advised to use between 20 to 30 mg per day, for an 8 to 10-week cycle.

Lastly, if you are recomposing, it is recommended that you use the dosages for bulking.


Well, that’s it for LGD-3303. Are you left thinking that this is too good to be true? Yeah, it happens a lot with this compound. But that’s because we’re used to anabolic compounds which are linked to some pretty nasty side effects. Who said bulking and cutting must be risky? Putting work in the gym is pretty hard as it is.

Anyway, LGD-3303 is another SARM to consider if you’ve decided you can’t do full natty and don’t want to mess with the nasty sides associated with steroids. 

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