Introduction to Andarine
There’s a new buzzword in the bodybuilding community. The chances are that you’ve come across the term SARMs being thrown around in various contexts. Better yet, have you heard the word Andarine pop up in a conversation? That must have sparked your curiosity. Anyway, if you gained some interest in Andarine, but couldn’t get a full scoop, you don’t have to worry because we’ve got you covered.
Honestly, there’s been some remarkable stories about Andarine, but also some not-so-good stories about the SARM. A while back, anecdotal reports of Andarine that it causes some vision-linked side effects started doing rounds. Initially, the reports were mostly about users seeing the wrong color and a yellowish shade to things; sort of like viewing the world in sepia. Anyway, good sense finally prevailed.
The following is a full scoop on everything Andarine, after which you will be equipped to make an informed decision on the popular SARM.
Andarine is in a category of substances known as SARMs (selective androgen receptor modulators). This compound was first researched by GTX laboratories for its possible therapeutic application in the treatment of benign prostatic hyperplasia, muscle wasting and osteoporosis. Another popular name for Andarine is S-4.
During the first clinical trials, it was found the Andarine possessed the prostate-selective SARM action, which implied that it could be used in the treatment of benign prostate hyperplasia. In particular, the SARM worked by blocking dihydrotestosterone from affecting receptors in the prostate.
At the time, researchers deemed Andarine a side-effect free alternative to drugs like Finasteride for managing BPH.
However, some concerns about some vision-related side effects arose, which led to the remaining research and development for Andarine being put on the backburner.
Given that Andarine is a partial agonist of the androgen receptor, it had a remarkable potential to promote the development of lean muscle mass, enhance strength, and stimulate lipolysis even when you aren’t working out.
The said three benefits are some of the most desired features by gym rats, bodybuilders and athletes alike. It goes without saying how Andarine ended up in the underground labs.
How does Andarine work?
Andarine is a selective androgen receptor modulator that functions by fusing with the androgen receptors in the skeletal and muscle tissues, sparing the reproductive and endocrine systems completely.
This SARM alters the gene expression, subsequently increasing protein synthesis and anabolism in the body. According to some rough projections, Andarine has about 35% of testosterone’s binding affinity. However, unlike testosterone, Andarine does not convert dihydrotestosterone into estrogen. Besides, Andarine was developed because it had an incredible ability to bind DHT from binding to prostrate receptors.
Andarine has excellent oral bioavailability, which means that after it is ingested, it can maneuver past the gastrointestinal system for absorption into the bloodstream without detection.
You can use Andarine during bulking, cutting and strength recomposition cycles. Besides, you use it for general personal wellness as well. If you stack it alone at 50 milligrams per day, you will experience some modest gains, including an increase in strength, lean muscle mass, and burning of fat. Anyway, below are some of the benefits associated with using Andarine.
You will hear the pros constantly comparing Andarine to Winstrol. Ever wondered why? That’s because, Andarine, just like Winny, can get you that competition ready physique. Do you get it? Like dry, ripped, popping muscles without fat or retained water.
In fact, most of the people who’ve used Andarine talks of achieving similar gains to what they got when they stacked with Anavar, Testosterone enanthate or Winstrol (anabolic steroids). Well not exactly, but it’s as close as you can get when using SARMs.
Here’s what to expect after using Andarine:
Andarine will make your muscles harder than before, and even more vascular, which makes it an excellent SARM for finishing. Considering that Andarine does not aromatize like the AS with which it is compared, you can rest assured that no water will be retained in your muscles. Therefore, within a fortnight or so, your muscles will feel harder and more defined. In a month, you will be shredded and ripped than ever.
Honestly, Andarine is not the de-facto choice for a strength increasing SARM. However, it’s one of the positives associated with the compound, and from the second week of using Andarine, you will experience a decent boost in your lifts. How cool is it to know that by week 5 of using Andarine, you will have broken your personal best? Well, some users have experienced it.
It appears that research and development for Andarine were shut down before it was made evident the exact way in which the SARM helps with fat burning. However, the most reasonable explanation is that Andarine (S4) suppresses the secretion of Hormone Sensitive Lipase (HSL). In doing so, it regulates the metabolism of stored fat.
Secondly, like other SARMs, it may also be the fact that SARMs tend to boost metabolism, which in turn, leads to burning of fat. The best part of it, you will not lose your muscle mass, which makes it excellent for cutting.
Gains in Muscle Mass
As it was mentioned earlier GTX, Andarine was first researched for its potential to prevent muscle wastage. Research findings show that Andarine has a remarkable potential to increase muscle mass in animals and humans too.
Andarine is an excellent SARM for bulking, and a majority of user reviews have indicated that one can experience some decent gains in mass even with little increases in mass. Moreover, this is a plus because it means you don’t have to lose your muscle mass when using Andarine for a cut.
Increased Bone Density
One of the primary therapeutic uses of Andarine was preventing bone loss and improving bone density. Given that Andarine binds to the androgen receptors in your bones too, you will experience an improvement in your bone density.
As a bodybuilder, weightlifter, it is the integrity of your bones that helps you to lift heavy. Moreover, enhanced bone density will also increase your range of motion and reduce your risk of fracture in sensitive joints.
Changes in Vision
The change in vision is the most talked about Andarine side effect. However, you should note that the claims that Andarine may cause peripheral blindness can only occur when the product is abused and overdosed.
However, Andarine does cause temporary changes in vision, which disappear as you come off the SARM. The most commonly experienced impact is experiencing a yellowish tinge to stuff. Moreover, you may also experience some difficulties when moving from a dark room to one that is well lit.
The important part is that these effects are temporary and will disappear after your cycle ends. Besides, you may never experience them if you stick to no more than 50 milligrams of Andarine daily.
Andarine tends to suppress the follicle stimulating hormone (FSH) and the luteinizing hormone (LH). Ass you may know, these two hormones are responsible for the production of testosterone and estrogen. As a result, upon using Andarine, you may experience temporary testosterone production.
As a result, it is advisable that you undergo a mini Post Cycle Therapy after completing your Andarine cycle.
Andarine is a Phase III non-steroidal selective androgen receptor modulator, aka receptor agonist (AR). It has a Ki of 4 NM and is tissue selective for anabolic organs.
You need to know that Andarine
is not a regulated product. This means that its identity and quality is often
questionable. Moreover, considering that its production had been stopped, you
must be very careful where you purchase Andarine. You can still buy Andarine as
a supplement, and if possible, always buy from a reputable website. That way,
you can ensure that you get the best quality and minimum risk of side effects.
Andarine has a very short half-life of about three to six hours. This means that you have to dose it frequently for lasting effects. While there is no set dosage for this drug, most users recommend 50 mg as the maximum Andarine dosage for the best results and minimum side effects.
If you are starting, don’t feel shy to begin with 25 mg daily, spread over two or three doses, and you can up the dose if you don’t get your desired results. At least you’ll be building tolerance for it as well.
That brings us to the end of our Andarine guide, but the remaining question is, is Andarine worth a shot? Let’s recap, so you have this product that increases muscle mass, enhances bone density, and helps with fat loss. Moreover, it’s excellent for bulking and cutting, and will give you that competition ready physique? How about the drawbacks? There must be a catch; for Andarine, you risk viewing your world in sepia mode, although temporarily and a reduction in your endogenous testosterone production.
Well, there’s been worse (side effects), but the benefits are pretty amazing if you ask a pro. Frankly, if you’ve considered dabbling in SARMs, then Andarine is definitely worth the shot, although you should make sure to buy from a reputable dealer.